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El-Sayed, M., . El-Tahan, ,., Lasheen, A. (2015). BENEFITING OF SOME PLANT MATERIALS IN IMPROVING LIVER FUNCTIONS FOR HEPATICALLY TOXICATED RATS WITH CCL4. Menoufia Journal of Food and Dairy Sciences, 40(3), 667-678. doi: 10.21608/mjfds.2015.323994
M. M. El-Sayed; , Nehad R . El-Tahan; Asmaa M. A. Lasheen. "BENEFITING OF SOME PLANT MATERIALS IN IMPROVING LIVER FUNCTIONS FOR HEPATICALLY TOXICATED RATS WITH CCL4". Menoufia Journal of Food and Dairy Sciences, 40, 3, 2015, 667-678. doi: 10.21608/mjfds.2015.323994
El-Sayed, M., . El-Tahan, ,., Lasheen, A. (2015). 'BENEFITING OF SOME PLANT MATERIALS IN IMPROVING LIVER FUNCTIONS FOR HEPATICALLY TOXICATED RATS WITH CCL4', Menoufia Journal of Food and Dairy Sciences, 40(3), pp. 667-678. doi: 10.21608/mjfds.2015.323994
El-Sayed, M., . El-Tahan, ,., Lasheen, A. BENEFITING OF SOME PLANT MATERIALS IN IMPROVING LIVER FUNCTIONS FOR HEPATICALLY TOXICATED RATS WITH CCL4. Menoufia Journal of Food and Dairy Sciences, 2015; 40(3): 667-678. doi: 10.21608/mjfds.2015.323994

BENEFITING OF SOME PLANT MATERIALS IN IMPROVING LIVER FUNCTIONS FOR HEPATICALLY TOXICATED RATS WITH CCL4

Article 2, Volume 40, Issue 3, June 2015, Page 667-678  XML PDF (456.43 K)
Document Type: original papers
DOI: 10.21608/mjfds.2015.323994
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Authors
M. M. El-Sayed; , Nehad R . El-Tahan; Asmaa M. A. Lasheen
Nutrition and Food Science, Faculty of Home Economics, Minufiya University
Abstract
ABSTRACT:The present study investigated the effects of carrot (Daucus carota, L.), prickly pear (Opuntia ficus-indica, L.) and chicory (Cichorium intybus, L.) on CCl4 induced hepatotoxicity in rats. Forty five male albino rats were divided into 9 groups (five rats in each group). Two groups were controls, one fed on basal diet only (negative control) and the other fed on basal diet after injection with CCl4 (positive control). The other groups were injected by CCl4 then received basal diet containing carrot, chicory and prickly pear at the levels 10, 15% and 15% mixture of the tested plants. Liver damage was assessed by estimation for the plasma concentration of enzymes activities of aspartate amino transferase (AST), alanine amino transferase (ALT), lipid fraction (total cholesterol and triglyceride), cholesterol fraction (HDL-c, LDL-c, VLDL-c), Uric acid, Urea nitrogen and glucose. Results showed an improvement in case of prickly pear followed by carrot and chicory for the above parameters.  The best level was 15% of these plants followed by 10% of tested plants. So, this study concluded that CCl4 induced liver damage in rats can be ameliorated by administration of 15% prickly pear, carrot and chicory.
Keywords
Carrot; prickly pear; chicory; liver damage; Cholesterol fraction; glucose
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